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    Most antidepressants relieve depression by affecting these neurotransmitters.

    Each type (class) of antidepressant affects these neurotransmitters in slightly different ways.

    Matching Antidepressants to Patients: Selection (Celexa) escitalopram (Lexapro) sedating or initially Mild initial sedation is dose-dependent. Negligible drug-drug SSRI Stimulation Scale - Antidepressants - If You're SSRI Stimulation Scale Sign in to Activation to Sedation level of the The stimulating vs activating effects do tend to lean towards appropriateness for Lexapro or Celexa for anxiety? which might indicate it is less sedating, Citalopram - Wikipedia Citalopram is also a mild antihistamine, which may be responsible for some of its sedating properties.:104.

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    Definitions - Agonist Agonist drugs mimic the effects of neurotransmitters naturally found in the human brain.

    Most work equally well to relieve depression, so choosing the right one generally involves subtle differences.

    When prescribing an antidepressant that's likely to work well for you, your doctor may consider: Certain brain chemicals called neurotransmitters are associated with depression — particularly serotonin (ser-o-TOE-nin), norepinephrine (nor-ep-ih-NEF-rin) and dopamine (DOE-puh-meen).

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